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. Author manuscript; available in PMC: 2018 Sep 19.
Published in final edited form as: Nature. 2017 Nov 8;551(7681):512–516. doi: 10.1038/nature24462

Extended Data Figure 4|. Unique genomic features alone do not identify long term survivors.

Extended Data Figure 4|

a, Overall survival of patients with tumors harboring greater or lesser than the median number of neoantigens (NeoantigenHi/Low), CD3-CD8 double positive cells (CD3-CD8Hi/Low), polyclonality (PolyclonalHi/Low), mutations (MutationHi/Low), and CD4 single positive cells (CD4Hi/Low). b, Oncoprint demonstrating no difference in the frequency of oncogenic driver mutations in short and long term tumors. c, No difference in the number of nonsynonymous, missense, and immunogenic mutations (neoantigens) in short and long term PDAC tumors. d, Overall survival stratified by mutations in ARID1A, KRASQ61H, RBM10, and MLL-related genes (MLL, MLL2, MLL3, MLL5). Horizontal bars, median values. n = biologically independent samples in individual patients. P-values were determined using log-rank test (a, d).