Table 1.
Clinic-pathologic and biologic data of the TNBC patients according to mutational status of PIK3CA
| Variables | Overall | PIK3CA wild type | PIK3CA mutated | P-value | ||||
|---|---|---|---|---|---|---|---|---|
| effective | % | effective | % | effective | % | |||
| Age range | < 40 | 11 | 28.2 | 9 | 23.07 | 2 | 5.1 | 0.542 |
| > 40 | 28 | 71.7 | 25 | 64.1 | 3 | 7.6 | ||
| Localization | Left breast | 30 | 76.9 | 25 | 64.1 | 5 | 12.8 | 0.09 |
| Right breast | 9 | 23.0 | 9 | 23.1 | 0 | 0 | ||
| Histopathologic type | Ductal carcinoma invasive | 33 | 84.6 | 29 | 74.3 | 4 | 10.2 | 0.729 |
| Lobular carcinoma invasive | 6 | 15.3 | 5 | 12.8 | 1 | 2.5 | ||
| Grade SBR | II | 12 | 30.7 | 10 | 25.6 | 2 | 5.1 | 0.639 |
| III | 27 | 69.2 | 24 | 61.5 | 3 | 7.6 | ||
| Ki67 | < 20% | 0 | 0 | 0 | 0 | 0 | 0 | 0.254 |
| 20–50% | 8 | 20.5 | 6 | 15.3 | 2 | 5.1 | ||
| > 50% | 31 | 79.4 | 28 | 71.7 | 6 | 15.3 | ||