Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 18;20:113. doi: 10.1186/s13058-018-1042-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 7 — Biodistribution and antitumor activity of nanoparticle-paclitaxel–small interfering RNA (NP-TAX–siRNA). a Ex vivo fluorescence imaging of major organs from MCF-7 tumor-bearing mice 10 h after intravenous injection with saline or Cy5.5-labeled NP-TAX–siRNA. b Mice bearing tumors were injected intravenously with different reagents (PBS, Blank NPs, Free siRNA, Free TAX, SP-siRNA, NP-TAX, and NP-TAX–siRNA) every other day from day 3 for a total of six injections. NP-TAX–siRNA treatment dramatically inhibited tumor growth compared with the control groups. Statistical analyses were performed by using a Kruskal–Wallis test followed by the Mann–Whitney test. *P <0.05 (n = 5–6). c Immunohistochemical staining of metadherin (MTDH) protein in tumor tissue in various treatment groups. Abbreviation: PBS phosphate-buffered saline