Figure 3.
TMEM119 knockdown inhibited SGC-7901 cell migration and invasion. TMEM119 mRNA and protein expression in SGC-7901 cells with TMEM119 siRNA transfection was measured by real-time PCR (A) and Western blotting (B and C). Cell migration and invasion (D and E), and protein expression of STAT3, p-STAT3, VEGF, MMP2, and MMP9 (F–H) in SGC-7901 cells after TMEM119 siRNA transfection was measured by transwell and Western blot analysis, respectively. **P<0.01 compared with scramble siRNA.
Abbreviation: PCR, polymerase chain reaction.