Table 3.

A summary of the time-saving software in the interpretation of SBCE

Study	Country	System	Study design	Summary of results
Hosoe et al 52	Japan (multicentre)	EndoCapsule: Omni mode	40 preselected cases (based on the presence of lesions) Each case was read twice in the Omni mode and twice in the normal mode	Reduction in average reading time from 75 to 27 min 65% reduction in displayed images Sensitivity of 87%
Subramanian et al 51	UK (single centre)	EndoCapsule: express selected/auto adjust	70 capsule cases Read in three modes: normal (15 fps), express selected+overview, adjusted mode+overview Each case read by two independent endoscopists	Normal: sensitivity of 100%, taking an average of 45 mins Express selected: sensitivity of 97.5%, an average 19 mins Auto adjust sensitivity of 97.5%, an average 34 mins
Kyriakos et al 49	Greece (single centre)	Pill Cam: QuickView	100 capsule studies pre-selected cases (based on the presence of lesions) Cases read in five different modes: normal at 10 fps, normal at 20 fps, normal mode with two images at 20 fps, automatic mode 10 fps and QuickView at 3 fps	All time-saving modes were faster than reading in normal mode at 10 fps Best compromise between speed and accuracy is normal mode at 20 fps, with either a single or dual image
Halling et al 47	Denmark (single centre)	Pill Cam: QuickView	Analysis of 12 video clips with findings 40 capsules of patients with suspected Crohn’s disease	Quickview missed 40% of ulcers seen in the normal viewing mode This effect is pronounced for terminal ileal lesions
Saurin et al 24	French (multi centre)	Pill Cam: QuickView	106 patients recruited across 12 centres Quickview vs normal mode reading	94% of significant lesions were identified Mean reading time of 11.6 mins using QuickView
Koulaouzidis et al 45	UK (single centre)	Pill Cam: QuickView	Retrospective review of 106 cases Normal mode vs Quickview vs Quickview with BM	Over 50% of ulcers missed in cases of suspect Crohn’s using QuickView 64% of potential/bleeding lesions were detected in the context of overt/occult bleeding
Shiotani et al 67	Japan (single centre)	Pill Cam: QuickView	100 capsule studies read in QuickView vs normal reading One nurse, two trainees and one experienced reader	Unacceptable miss rate Miss rate was greatest in the physicians with limited experience
Hosoe et al	Japan (single centre)	Pill Cam: QuickView	45 capsule studies Gold-standard reading established by two experienced readers Three trainees with no prior capsule experience read in normal mode, automatic mode and QuickView	Reduced reading time in automatic and QuickView compared with normal mode 179 missed lesions when using QuickView
Westerhof et al 50	Netherlands (single centre)	Pill Cam: QuickView	200 cases included First 100 read in the normal mode and then only alternate images Second 100 read in the normal mode then with QuickView	Normal mode average reading time of 17 mins Miss rate of 4% when viewing alternate images Avreage reading time of 10 mins Miss rate of 13% with QuickView Average reading time of 4.4 mins
Xu et al 68	China (single centre)	OMOM: similar picture elimination	Retrospective study of 148 capsule studies Read in five modes: normal, level I, level II, level III and level IV Each case read by four independent endoscopists	Reading time reduction of 25.1%–55.0% compared with normal mode Normal: sensitivity of 93.8% Mode I: sensitivity of 87.7% Mode II: sensitivity of 77.8% Mode III: sensitivity of 70%

SBCE, small bowel capsule endoscopy.