Table 1.

Pooled Echocardiographic Data From the 2 Mouse Genotypes Under Basal Conditions (Before MI) and 1 Month Post-MI

	Baseline			Post-MI
	Cre	mGATA3KO	p Value	Cre	mGATA3KO	p Value
Number of animals	5	6		6	6
Heart rate	405 ± 19	423 ± 14	NS	443 ± 27	425 ± 17	NS
EF (%)	63.3 ± 0.2	63.4 ± 0.8	NS	44.2 ± 1.9	53.81+1.1	<0.001
FS (%)	33.7 ± 0.1	33.7 ± 0.6	NS	21.8 ± 1.1	27.4 ± 0.7	0.002
EDV (μl)	58.7 ± 2.1	56.4 ± 1.8	NS	82.5 ± 6.3	67.27 ± 2.2	0.04
ESV (μl)	21.9 ± 0.7	20.7 ± 0.9	NS	82.5 ± 6.3	67.2 ± 2.2	0.04

Values are mean percent changes over baseline.

EDV = end-diastolic volume; EF = ejection fraction; ESV = end-systolic volume; FS = fractional shortening; mGATA3KO = myeloid-specific GATA3 knockout mouse; MI = myocardial infarction; NS = not significant.