Table 2.

Echocardiographic Assessment and Heart Mass Ratios of the 2 Mouse Genotypes 2 Months Post-TAC

	Cre	mGATA3KO	p Value
Number of animals	8	6
Heart rate	426 ± 36	435 ± 18	NS
EF (%)	41.3 ± 0.9	50.6 ± 0.4	<0.0001
FS (%)	20.9 ± 0.6	25.3 ± 0.2	0.0002
ESV	52.5 ± 2.0	33.5 ± 1.1	<0.0001
EDV	92.8 ± 3.3	67.2 ± 1.8	<0.0001
LVPWTs	1.05 ± 0.01	0.93 ± 0.02	<0.001
LVPWTd	0.84 ± 0.01	0.70 ± 0.02	<0.0005
HW/BW	5.8 ± 0.3	4.5 ± 0.1	<0.02

Values are mean ± SD. HW/BW at baseline for Cre and mGATA3KO mice were 4.1 ± 0.14 and 3.99 ± 0.15, respectively.

HW/BW = heart weight per body weight ratio; LVPWTd = LV posterior wall thickness diastolic; LVPWTs = left ventricular posterior wall thickness systolic; TAC = transverse aortic constriction. Other abbreviations as in Table 1.