Fig 6. Haplotypes produced in the F2 breakdown, assuming a single recombination event, explain how different linkage architectures leads to different outcomes for the same loci.

By identifying the relatively “epistasis-free” haplotype formed, one can infer whether hybrid speciation may be a likely outcome. In blue, we highlight these “epistasis-free” haplotypes that are important for hybrid speciation and in yellow those that are important for fixation of the parental haplotype from population 1.