Table 2. Base Case Results.
| Strategy | Fraction of Life-Years With Depression Outcome, % | QALYs per Patient | Healthcare Costs per Patient, 2013 US $ | Incremental Cost-effectiveness Ratio (US $/QALY) | ||||
|---|---|---|---|---|---|---|---|---|
| Remission | Response | Nonresponsea | Totalb | ECT | Other | |||
| ECT | ||||||||
| None | 42.5 | 7.3 | 50.2 | 2.63 | 42 490 | NA | 42 490 | NA |
| Sixth-line | 52.2 | 10.7 | 37.1 | 2.75 | 50 080 | 9090 | 40 990 | Dominated |
| Fifth-line | 53.0 | 11.0 | 36.1 | 2.76 | 49 850 | 9910 | 39 930 | Dominated |
| Fourth-line | 53.6 | 11.4 | 35.1 | 2.76 | 50 900 | 10 900 | 40 000 | Dominated |
| Third-line | 53.8 | 12.1 | 34.1 | 2.77 | 49 830 | 12 220 | 37 610 | 54 000 |
| Second-line | 53.8 | 12.7 | 33.5 | 2.77 | 52 000 | 14 610 | 37 390 | 564 000 |
| First-line | 53.8 | 13.3 | 32.9 | 2.78 | 54 520 | 17 130 | 37 390 | 815 000 |
Abbreviations: ECT, electroconvulsive therapy; QALYs, quality-adjusted life-years.
a
Includes the model states nonresponse, relapse, and initiation.
b
Due to rounding, the total cost presented does not equal the sum of the ECT and other subcategories for certain strategies.