| RPL21P28 |
-1.70 |
Ribosome large subunit protein |
| RPL21 |
-1.50 |
Ribosome large subunit protein, association with increased cMyc expression |
| BIRC5 |
-1.48 |
cIAP5, survivin, inhibitor of apoptosis, driver of DNA damage drug resistance |
| RPL27A |
-1.47 |
Ribosome large subunit protein |
| RPL9 |
-1.37 |
Ribosome large subunit protein |
| BIRC3 |
-1.35 |
cIAP2 protein, inhibitor of apoptosis, driver of DNA damage drug resistance |
| RPS15A |
-1.35 |
Ribosome small subunit protein |
| RPS21 |
-1.28 |
Ribosome small subunit protein |
| RPS19 |
-1.21 |
Ribosome small subunit protein, higher expression linked to certain carcinomas and Diamond-Blackfan anemia |
| PHF5A |
-1.17 |
Involved in splicing factor 3b complex, transcriptional elongation, pluripotency maintenance |
| SPATA2 |
-1.17 |
Recruits and activates deubiquitinases, regulates inflammatory signaling, loss promotes necroptosis by TNF |
| RPL11 |
-1.10 |
Ribosome large subunit protein, blocks mdm2 degradation of p53, involved in cell cycle arrest during stress, DDR |
| RPL22L1 |
-1.03 |
Ribosome large subunit protein, regulates pre-mRNA splicing, ribosome biogenesis |
| CCN1/CYR61 |
-1.07 |
Promotes cancer cell survival, proliferation, angiogenesis |
| AVEN |
-0.96 |
Inhibitor of caspases and apoptosis, blocks cell cycle during DDR, loss promotes genomic instability and cell death |
| BECN1 |
-0.90 |
Binds BCL2, promotes ovarian cancer and evades apoptosis with increased autophagy |
| RPL17 |
-0.90 |
Ribosome large subunit protein, involved in large subunit biogenesis |
| PNO1 |
-0.90 |
Involved in 18S rRNA processing, ribosomal and proteasome biogenesis |
| RPL23A |
-0.88 |
Ribosome large subunit protein |
| PIGA |
-0.87 |
Involved in GPI anchor adhesion, GPI function in signaling |
| RPS3A |
-0.83 |
Ribosome small subunit protein, overexpression associated with carcinoma |
| METAP2 |
-0.83 |
Promotes N-terminal methionine removal, angiogenesis, prevents eIF2α phosphorylation and inhibition of protein synthesis during cell stress |
| RPL37 |
-0.83 |
Ribosome large subunit protein, overexpressed in certain cancers |
| CAAP1 |
-0.80 |
Caspase and apoptosis inhibitor |
