Table 2. Expert Dermatologist Diagnoses Following Their Review of Cases Initially Reported as Cutaneous Adverse Drug Reactions Irrespective of Causative Drug.
| Adverse Eventa | Patients, No. | Total | |||||
|---|---|---|---|---|---|---|---|
| Positive for HLA-A*31:01b | Negative for HLA-A*31:01 | ||||||
| Possible | Unlikely | Definite | Probable | Possible | Unlikely | ||
| Drug-induced hypersensitivity syndrome | 0 | 0 | 2 | 1 | 0 | 0 | 3 |
| Maculopapular eruption | 0 | 2 | 5 | 4 | 4 | 1 | 16 |
| Erythema multiforme | 0 | 0 | 4 | 1 | 2 | 0 | 7 |
| Other | 0 | 0 | 0 | 0 | 0 | 4 | 4 |
| Unknown | 1 | 1 | 0 | 6 | 3 | 6 | 17 |
| Total | 1 | 3 | 11 | 12 | 9 | 11 | 47 |
a
No patient developed Stevens-Johnson syndrome, toxic epidermal necrolysis, or fixed drug eruption.
b
No HLA-A*31:01–positive patient developed a definite or probably adverse event.