Figure. Forest Plot of the Association Between Sickle Cell Trait (SCT) Status and Incidence of Stroke in the 4 African American Cohorts.

The fully adjusted Cox proportional hazards regression model (adjusted model 3) is shown. Weights are from random-effects analysis. Boxes indicate hazard ratios (HRs); error bars, 95% CIs; and diamond, overall results. HR indicates hazard ratio; JHS, Jackson Heart Study; MESA, Multi-Ethnic Study of Atherosclerosis; REGARDS, Reasons for Geographic and Racial Differences in Stroke; and WHI, Women’s Health Initiative.