Table 3. Univariate Association of Demographic and Clinical Variables With Suicide Deatha.
Demographic | Suicide Death, HR (95% CI) | ||
---|---|---|---|
Years 1-3 (n = 34) | Years 4-12 (n = 39) | 12 Years (n = 73) | |
Age at onset | 0.99 (0.90-1.09) | 1.02 (0.92-1.13) | 1.01 (0.94-1.08) |
Educational level | 0.94 (0.83-1.06) | 0.89 (0.78-1.00)b | 0.91 (0.84-0.99)b |
Sex (reference group: female) | 1.34 (0.69-2.63) | 1.70 (0.88-3.31) | 1.52 (0.94-2.47) |
Baseline variables | |||
DUP, d | 1.09 (0.86-1.38) | 1.00 (0.83-1.20) | 1.04 (0.89-1.21) |
Baseline positive symptoms | 1.03 (0.65-1.64) | 0.97 (0.70-1.35) | 1.00 (0.76-1.31) |
Baseline negative symptoms | 0.96 (0.74-1.24) | 1.10 (0.85-1.41) | 1.03 (0.86-1.23) |
Baseline affective symptoms | 1.11 (0.83-1.47) | 0.94 (0.70-1.28) | 1.02 (0.83-1.26) |
Premorbid occupational impairment (reference group: not impaired) | 0.76 (0.18-3.17) | 2.69 (1.17-6.13)b | 1.72 (0.85-3.45) |
No. of suicide attempts during DUP | 1.64 (1.24-2.17)c | 1.32 (0.89-1.96) | 1.48 (1.18-1.86)c |
Variables of the first 3 y | |||
No. of suicide attempts | 1.95 (1.39-2.73)c | 1.50 (0.96-2.34) | 1.72 (1.30-2.78) |
No. of hospitalization | 1.00 (0.96-1.05) | 1.03 (0.98-1.08) | 1.02 (0.98-1.05) |
No. of relapse | 0.95 (0.70-1.28) | 1.34 (1.03-1.75)a | 1.17 (0.95-1.43) |
Adherence | 1.63 (0.79-3.34) | 2.55 (1.32-4.94)d | 2.11 (1.31-3.40)d |
Presence of substance abuse (reference group: no substance abuse) | 0.56 (0.19-1.59) | 0.89 (0.28-2.80) | 0.70 (0.32-1.53) |
Mean DDD | 0.85 (0.44-1.67) | 1.10 (0.70-1.72) | 0.98 (0.67-1.45) |
Abbreviations: DDD, defined daily dose; DUP, duration of untreated psychosis; HR, hazard ratio.
Cox proportional hazards regression was used accounting for correlated groups of observations.
P < .05.
P < .001.
P < .01.