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. 2018 Apr 4;75(5):458–464. doi: 10.1001/jamapsychiatry.2018.0185

Table 3. Univariate Association of Demographic and Clinical Variables With Suicide Deatha.

Demographic Suicide Death, HR (95% CI)
Years 1-3 (n = 34) Years 4-12 (n = 39) 12 Years (n = 73)
Age at onset 0.99 (0.90-1.09) 1.02 (0.92-1.13) 1.01 (0.94-1.08)
Educational level 0.94 (0.83-1.06) 0.89 (0.78-1.00)b 0.91 (0.84-0.99)b
Sex (reference group: female) 1.34 (0.69-2.63) 1.70 (0.88-3.31) 1.52 (0.94-2.47)
Baseline variables
DUP, d 1.09 (0.86-1.38) 1.00 (0.83-1.20) 1.04 (0.89-1.21)
Baseline positive symptoms 1.03 (0.65-1.64) 0.97 (0.70-1.35) 1.00 (0.76-1.31)
Baseline negative symptoms 0.96 (0.74-1.24) 1.10 (0.85-1.41) 1.03 (0.86-1.23)
Baseline affective symptoms 1.11 (0.83-1.47) 0.94 (0.70-1.28) 1.02 (0.83-1.26)
Premorbid occupational impairment (reference group: not impaired) 0.76 (0.18-3.17) 2.69 (1.17-6.13)b 1.72 (0.85-3.45)
No. of suicide attempts during DUP 1.64 (1.24-2.17)c 1.32 (0.89-1.96) 1.48 (1.18-1.86)c
Variables of the first 3 y
No. of suicide attempts 1.95 (1.39-2.73)c 1.50 (0.96-2.34) 1.72 (1.30-2.78)
No. of hospitalization 1.00 (0.96-1.05) 1.03 (0.98-1.08) 1.02 (0.98-1.05)
No. of relapse 0.95 (0.70-1.28) 1.34 (1.03-1.75)a 1.17 (0.95-1.43)
Adherence 1.63 (0.79-3.34) 2.55 (1.32-4.94)d 2.11 (1.31-3.40)d
Presence of substance abuse (reference group: no substance abuse) 0.56 (0.19-1.59) 0.89 (0.28-2.80) 0.70 (0.32-1.53)
Mean DDD 0.85 (0.44-1.67) 1.10 (0.70-1.72) 0.98 (0.67-1.45)

Abbreviations: DDD, defined daily dose; DUP, duration of untreated psychosis; HR, hazard ratio.

a

Cox proportional hazards regression was used accounting for correlated groups of observations.

b

P < .05.

c

P < .001.

d

P < .01.