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. 2017 Dec 21;20(3):207–214. doi: 10.1001/jamafacial.2017.1888

Table 1. In-depth Analysis of Serious Complications of Filler Injections.

Location and Type of Filler No. (%)a
Arterial Only Blindness Necrosis Total No. of Injections
Location
Lip 81 (15.4) 0 35 (6.7) 525
Nasolabial fold 63 (14.7) 0 36 (8.4) 428
Cheek 51 (6.8) 0 3.2 (24) 751
Marionette line 13 (6.9) 0 7 (3.7) 189
Periorbital 0 4 (2.9) 3 (2.2) 137
Forehead 12 (13.3) 3 (3.3) 16 (17.7) 90
Dorsal aspect of nose 0 1 (16.7) 0 6
Fillerb
Hyaluronic acid 151 (9.4) 7 (0.4) 136 (8.5) 1605
Sculptra 4 (8.5) 0 2 (4.3) 47
Radiesse 27 (28.1) 1.0 (1.0) 29 (30.2) 96
a

Percentages indicate the fraction in that specific location or for that specific filler only. P < .001 for all comparisons.

b

Sculptra (poly-L-lactic acid), Sanofi; Radiesse (calcium hydroxylapatite), Merz Pharmaceuticals).