Table 3.
Association between children’s antibiotic prescription strategies and reconsulting for the same RTI illness with evidence of deterioration in the 30 days following the baseline consultation
| No reconsultation | Reconsulted for deterioration | Univariable analysis clustering by clinician | Multivariable analysis accounting for where P<0.05 and clustering by clinician | Analysis stratified by propensity score and accounting for clustering by clinician | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | % | n | % | RR | 95% CI | P-valuea | RR | 95% CI | P-valuea | RR | 95% CI | P-valuea | |
| No antibiotic | 4864/7786 | 62.5 | 240/350 | 68.6 | Ref | Ref | 0.008 (2 df) | Ref | Ref | 0.007 (2 df)b | Ref | Ref | 0.024 (2 d.f) |
| Immediate | 2175/7786 | 27.9 | 91/350 | 26.0 | 0.85 | 0.67 to 1.09 | 0.78 | 0.61 to 0.99 | 0.82 | 0.65 to 1.07 | |||
| Delayed | 747/7786 | 9.6 | 19/350 | 5.4 | 0.52 | 0.32 to 0.87 | 0.56 | 0.34 to 0.91 | 0.55 | 0.34 to 0.88 | |||
a
Overall P-value.
b
Covariates included (P<0.05): moderate/severe vomiting in the 24 hours before baseline, white ethnicity, age<(2 years), short< (3 days) illness duration prior to baseline, clinician-reported wheeze, parent-reported disturbed sleep in the previous 24 hours, moderate or severe vomiting and severe blocked nose in the previous 24 hours. df = degrees of freedom. Ref = reference. RR = risk ratio.