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. Author manuscript; available in PMC: 2019 Sep 19.
Published in final edited form as: Nat Prod Rep. 2018 Sep 19;35(9):847–878. doi: 10.1039/c8np00013a

Fig. 15.

Fig. 15

(a) Biosynthesis of the sorbicillin natural products, including sorbicillactone A, involves cyclization of a hexaketide to the sorbicillin intermediate following TR-mediated release from the nonreducing iterative PKS complex, (b) Structure of bisvertinolone. (c) Structure of bisorbicillinol. (d) Structure of trisorbicillinone A.