Table 3.
Initial rates of O2 consumption and CAD hydroxylation for the different D201X variants. All values are in min−1 units. None of the other (FeII/αKG) variants consume O2.
| wt-FIH | 16.3 ± 0.7 | 15.4 ± 0.6 |
| D201GCl | 1.9 ± 0.4 | 0.41 ± 0.03 |
| D201G | 0.3 ± 0.1 | 0.16 ± 0.01 |
| D201E | 1.7 ± 0.1 | 0.16 ± 0.02 |
| D201A | <0.01 | Not Detectable |
| D201E (No CAD) | 1.67 ± 0.08 | N/A |