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. Author manuscript; available in PMC: 2019 Aug 6.
Published in final edited form as: J Surg Oncol. 2018 Aug 6;118(2):253–264. doi: 10.1002/jso.25150

Figure 3.

Figure 3

In vivo detection of recurrent tumors after fluorescence-guided surgery. (A) Brightfield observation several weeks after fluorescence-guided surgery of OBP-401 GFP-labeled tumors. Disseminated disease re-emerged. (B) Fluorescence observation of field observed by brightfield in (A). (C) Merge of (A and B). The red box outlines a region of (D) below. (D) Detail of the boxed region of (C). Black line indicates the direction of cross-sections. (E) Histologic sections stained with H&E showing that GFP-labeled lesions are recurrent tumor tissues (arrow heads). ×40 magnification. (F) Detail of the boxed region of (E). ×200 magnification.[59]