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. 2018 Sep 13;9:1996. doi: 10.3389/fimmu.2018.01996

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Copyright © 2018 Pal Singh, de Bruijn, de Almeida, Meijers, Nitschke, Langerak, Pillai, Stadhouders and Hendriks.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CLL V_H11 usage is dependent on antigenic stimulation. (A) Kaplan-Meier incidence curves of IgH.TEμ (dotted line) vs. IgH.TEμ.TD (solid line). (B) Pie charts summarizing the frequencies of V_H11 (gray) and non-V_H11 BCR-expressing CLL in the indicated mouse groups.