Skip to main content
. 2018 Sep 13;9:2079. doi: 10.3389/fimmu.2018.02079

Figure 4.

Figure 4

The gut microbiota plays a protective role during CLP-induced sepsis in mice. (A) The survival of none-treat WT and Gpr109a−/– mice, andantibiotic treated WTand Gpr109a−/– mice which undergo the CLP surgery (n ≥ 30)), **p < 0.01. (B) Overall survival rate of none-treat WT and Gpr109a−/– mice, and microbiota-transferred WT and Gpr109a−/– mice which undergo the CLP surgery (n = 14). (C) Weight loss of none- and CLP-treated WT and Gpr109a−/− mice (n = 7 ~ 9). (D) Clinical score of none- and CLP-treated WT and Gpr109a−/− mice (n = 7 ~ 9), *p < 0.05. (E) Colon lengths of different treatment mice (n = 7 ~ 9). (F,G) The expression of IL-6 and IL-1β mRNA in colon tissue homogenate from different treatment mice (n = 3).