Figure 5. miR-206 suppresses CRC cell proliferation and induces cell apoptosis by targetting TM4SF1 in PGE2-induced cells.

(A) HCT116 and Caco-2 cells were transfected with miR-206 or TM4SF1 and treated with PGE2 for the indicated time. MTT assay was used to investigate the effect of miR-206 on the proliferation of PGE2-induced cells. (B) Apoptotic cells were determined using flow cytometry analysis. The data are presented as mean ± standard error. *P<0.05 compared with control.