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. 2018 Sep 19;38(5):BSR20180664. doi: 10.1042/BSR20180664

Figure 8. The effect of miR-206 overexpression can be reversed by the induction of TM4SF1 in PGE2-induced cells.

Figure 8

(A) HCT116 and Caco-2 cells were transfected with miR-206 or TM4SF1 and treated with PGE2 for 12 h. E-cadherin, β-catenin, VEGF, MMP-9, Snail, and Vimentin were detected. (B) The expression of p-AKT, AKT, p-ERK, PCNA, an β-actin loading control using Western blot analysis. (C) Schematic illustration of the proposed mechanism of miR-206-mediated inhibition of TM4SF1 in PGE2-induced colon cancer cells.