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(A) Western blotting result of caspase-3, caspase-12 in the brain lining tissue. (B,D) TUNEL result of apoptosis in cerebrovascular endothelial cells. (C,E) Immunohistochemistry of GRP78 of cerebrovascular tissue (**P<0.01, compared with control; #P<0.05, ##P<0.01 compared with Wilson; @P<0.05, @@P<0.01 compared with Penicillamine).
