Table 1. Antimicrobial activity of linear TriA1 analogues.
| ||||
Peptide | Amino acid |
MIC
a
|
||
5 | 9 | E. coli b | S. aureus c | |
1 | d-Trp | Phe | 0.39 | 25 |
2 | d-Agl | Agl | >50 | >50 |
3 | d-Sac | Sac | >50 | >50 |
4 | d-Cys | Cys | >50 | >50 |
aMIC = minimum inhibitory concentration. Determined by microbroth dilutions assays and experiments run in duplicate. Values are shown to two significant figures and reported in μg mL–1.
bStrain NCTC 12241.
cStrain NCTC 10788.