Fig. 4. Characterization of HA hydrogels loaded with nioplexes. (A) The mechanical properties of the hydrogels were determined using plate-to-plate rheometry over a frequency range of 0.1–10 rad s−1 at a constant strain of 0.01. (B) Average storage modulus. (C–F) Particle distribution in hydrogels 1 (C), 2 (D), 3 (E) and 4 (F). Gel ID: 1, control hydrogel without nioplexes; 2, 0.055 μg DNA per μl; 3, 0.12 μg DNA per μl and 4, 0.2 μg DNA per μl. Scale bars: 200 μm.
