Table 3.
Mean and standard deviation for the morphological parameters of SHAM and GIO samples.
| SHAM | GIO | p | |
|---|---|---|---|
| Number of donors | 5 | 4 | – |
| Number of samples | 5 | 6 | – |
| Total number of lacunae | 6 | 15 | – |
| Lc.V1 [μm3] | 200 ± 40 (n = 5) | 168 ± 79 (n = 12) | 0.41 |
| Lc.V2 [μm3] | 213 ± 44 (n = 6) | 170 ± 79 (n = 15) | 0.23 |
| Lc.An12 | 0.49 ± 0.16 (n = 6) | 0.61 ± 0.21 (n = 15) | 0.19 |
| Lc.An13 | 0.199 ± 0.113 (n = 6) | 0.289 ± 0.15 (n = 15) | 0.102 |
| Lc.Fopt [μm] | 0.41 ± 0.10 (n = 6) | 0.72 ± 0.27 (n = 15) | 0.0064** |
| Ca.V/MV (microporosity) | 0.025 ± 0.010 (n = 5) | 0.020 ± 0.009 (n = 5) | 0.45 |
| Ca.Dm [nm] | 165 ± 8 (n = 4) | 152 ± 6.5 (n = 4) | 0.053 |
| Ca.Nb [μm−2] | 0.36 ± 0.09 (n = 6) | 0.24 ± 0.07 (n = 12) | 0.0106* |
| Ca.Pr | near to 80 (n = 6) | near to 80 (n = 15) | >0.05 |
| Ca.Db [μm] | near to 1.1 (n = 6) | near to 1.1 (n = 15) | >0.05 |
Lc = lacuna; Ca = canaliculi; TV = tissue volume; V₁, V₂ = lacuna volumes computed by methods 1 and 2 described in Materials and Methods; An12, An13 = degrees of anisotropy; Ca.Dm = canaliculi diameter, Lc.Fopt = optimization function; Ca.V/MV = microporosity as the ratio of the volume occupied by canaliculi to the total matrix tissue volume; Ca.Nb = number of canaliculi originating from the lacuna per ellipsoidal surface unit; Ca.Pr = mean number of primary canaliculi directly connected to the lacuna; Ca.Db = length of the first dendritic branching distance. In the right column, the p value from the Wilcoxon-Mann-Whitney test is given, and significant differences are indicated (*, p < 0.05; **, p < 0.01).