Table 1.
Demographic variables | Fontan (N=164) | Control (N=82) | p |
---|---|---|---|
Age, years | 36 (25–43) | 45 (35 – 52) | <0.001 |
Male | 88 (54%) | 26 (32%) | 0.01 |
Body mass index, kg/m2 | 27 ± 3 | 28 ± 6 | 0.12 |
Body surface area, m2 | 1.9 ± 03 | 1.9 ± 0.2 | 0.31 |
Laboratory data | |||
Hemoglobin, g/dl | 15.1 ± 0.4 | 13.3 ± 0.6 | 0.01 |
Albumin, g/dl | 4.2 ± 0.4 | 4.4 ± 0.6 | 0.23 |
Creatinine, mg/dl | 1.1 ± 0.4 | 0.9 ± 0.2 | 0.18 |
NT-pro BNP, pg/ml | 191 (114 – 746) | 47 (25 – 82) | <0.001 |
Estimated plasma volume, ml | 2971± 423 | 2703 ± 311 | 0.06 |
Medications | |||
Diuretics | 45 (27%) | 14 (18%) | 0.12 |
RAAS antagonist | 46 (28%) | 15 (19%) | 0.13 |
Beta blockers | 31 (20%) | 20 (24%) | 0.56 |
Comorbidities | |||
Hypertension | 1 (1%) | 32 (39%) | <0.001 |
Hyperlipidemia | 42 (26%) | 26 (32%) | 0.21 |
Diabetes | 14 (9%) | 5 (6%) | 0.41 |
NT-pro BNP: N-terminal pro-B-type natriuretic peptide; RAAS: Renin angiotensin aldosterone system antagonist