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. 2018 Sep 19;18:144. doi: 10.1186/s12935-018-0639-3

Table 2.

Cox model analysis for the correlation between RIG-I expression and patients’ clinical parameters

Clinical parameters Uni-variate Multi-variate
HR (95% CI) P HR (95% CI) P
Gender (M/F) 0.924 (0.528–1.616) 0.781 0.733 (0.399–1.350) 0.319
Age (years) (≥ 60/< 60) 1.391 (0.736–2.536) 0.281 1.916 (1.010–3.636) 0.047
Tumor size (≥ 5 cm/< 5 cm) 1.726 (0.999–2.984) 0.051 1.077 (0.575–2.017) 0.816
Pathological stage (III + IV/I + II) 1.961 (0.883–4.355) 0.098 0.860 (0.358–2.067) 0.860
Tumor stage (T3 + T4/T1 + T2) 2.564 (0.923–7.127) 0.071 1.705 (0.588–4.941) 0.326
Lymph node metastasis (yes/no) 2.494 (1.170–5.314) 0.018 1.837 (0.621–5.437) 0.272
Distant metastasis (yes/no) 2.547 (1.187–5.466) 0.016 2.117 (0.907–4.940) 0.083
TNM stage (III + IV/I + II) 3.017 (1.620–5.617) 0.000 2.503 (1.047–5.980) 0.039
RIG-I expression (High/low) 0.400 (0.226–0.708) 0.023 0.404 (0.210–0.777) 0.007