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. 2018 Sep 19;13:164. doi: 10.1186/s13023-018-0906-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Hormones, G Ratio and gene correlations in galactosaemia. The strength of the association is denoted by r_s (Spearman’s ρ), 1 being a perfect positive correlation, − 1 being a perfect negative correlation. The p-value (2-tailed) for the association is indicated. The sloping line is the best fit line and indicates the direction of the correlation. a FSH levels correlate positively with BMI corrected leptin in the CG combined group (n = 28: r_s = 0.445, p < 0.05). b ALG9, LEP and MGAT3 expression correlate negatively with G-ratios (G0/G1) in CG females (ALG9: n = 18, r_s = − 0.600, p < 0.01. MGAT3: n = 13, r_s = − 0.687, p < 0.05. LEP: n = 6, r_s = − 0.943, p < 0.01). c LH levels correlate positively with G-ratios (G0/G1) in CG females (n = 18, r_s = 0.529, p < 0.05). d LH levels correlate positively with G-ratios (G0/G2) in CG females (n = 18, r_s = 0.608, p < 0.01)