Table 3.
Serum Leptin levels in CG vs healthy controls and correlations with hormone, G-ratios and ANXAI gene expression
| Serum Leptina | |||||
|---|---|---|---|---|---|
| Gender | Group | n= | Mean ± SD | Range | p-value |
| Male | CG | 18 | 2.6 ± 1.86 | 0.10–6.60 | 0.031 |
| Healthy Control | 10 | 7.40 ± 5.60 | 0.70–18.80 | ||
| Female | CG | 19 | 13.22 ± 9.47 | 1.18–33.12 | 0.099 |
| Healthy Control | 10 | 20.10 ± 12.53 | 3.60–45.44 | ||
| Spearman Correlations - Serum Leptin Corrected for BMIb | |||||
| Variable 1 | Variable 2 | Gender | n= | p-value | Correlation Coefficient |
| Leptin, BMI corrected | G0/G1 | Male and Female | 26 | 0.0001 | − 0.681 |
| Leptin, BMI corrected | G0/G2 | Male and Female | 26 | 0.002 | − 0.588 |
| Leptin, BMI corrected | Testosterone | Male | 11 | 0.026 | 0.664 |
| Leptin, BMI corrected | FSH | Male and Female | 25 | 0.027 | 0.441 |
| Leptin, BMI corrected | ANXA1 | Female | 17 | 0.012 | 0.593 |
aLeptin data was available for 37 of 54 patients. The p-values of this section show results of the difference in means of serum leptin levels in CG vs healthy control (Mann Whitney U test)
bCorrelations between serum leptin corrected for BMI vs other variables in combined and separate gender cohorts