Fig. 2.

Parameters of vigilance state consolidation/fragmentation in Nlgn2^+/+, Nlgn2^+/− and Nlgn2^−/− mice quantified for the 12 h Light and the 12 h Dark periods using EEG and EMG recordings. a) Mean duration of individual episodes of vigilance states. Significant genotype effect was found for 12 h Light NREM sleep (F_2,37 = 4.3, p = 0.02) and 12 h Dark wake (F_2,37 = 4.9, p = 0.01). No significant genotype effect was found for 12 h Light wake (F_2,37 = 3.2, p = 0.052), 12 h Light REM sleep (F_2,37 = 0.2, p = 0.8), 12 h Dark NREM sleep (F_2,37 = 1.1, p = 0.3), and 12 h Dark REM sleep (F_2,37 = 0.1, p = 0.9). b) Number of individual episodes of vigilance states. Significant genotype effects were observed for all states for both the 12 h Light and 12 h Dark (12 h Light wake F_2,37 = 3.6, p = 0.04; 12 h Light NREM sleep F_2,37 = 3.5, p = 0.04; 12 h Light REM sleep F_2,37 = 3.3, p = 0.048; 12 h Dark wake F_2,37 = 4.3, p = 0.02; 12 h Dark NREM sleep F_2,37 = 4.2, p = 0.02; 12 h Dark REM sleep F_2,37 = 3.5, p = 0.04). Stars show significant post-hoc Tukey HSD comparisons between indicated genotypes (*: p < 0.05; **: p < 0.01). Grey backgrounds indicate the 12 h dark period