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. 2018 Aug 29;92(18):e01115-18. doi: 10.1128/JVI.01115-18

FIG 2.

FIG 2

N-glycan microarray binding profiles of canine influenza A virus (CIV) and CIV-derived mutant viruses to representative linear and branched glycans. (A) wt–cH3N8. (B) rg-54N–cH3N8. (C) rg-83N–cH3N8. (D) rg-222W–cH3N8. (E) Pennsylvania-eH3N8. Viruses are indicated at the top of figure panels. The data are the mean fluorescent binding signal intensities ± the standard deviations (vertical bars). (F) Representative glycan structures on the isoform N-glycan microarray. N002-N122, Neu5Acα2,3 glycans; N003-N123, Neu5Acα2,6 glycans; N005-N255, fucosylated Neu5Acα2,3 glycans; N12G-N22G, Neu5Gcα2,3 glycans; N015G-N025G, fucosylated Neu5Gcα2,3 glycans. Neu5Ac, N-acetyl neuraminic acid; Neu5Gc, N-glycolylneuraminic acid. The structure details of these glycans are listed in Fig. S1 in the supplemental material.