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. 2018 Aug 29;92(18):e00755-18. doi: 10.1128/JVI.00755-18

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Copyright © 2018 Lupey-Green et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 5 — Active chromatin landscape at the Cp promoter is repressed after PARP inhibition. (A) Methylated DNA immunoprecipitation (MeDIP) qPCR at the Cp promoter in untreated and olaparib-treated (PARPi) LCLs. qPCR data are presented as percentages of input DNA. Results are representative of three independent experiments and show means ± standard deviations. (B) ChIP-qPCR for the repressive H3K27me3 mark at Cp in untreated and olaparib-treated (PARPi) LCLs. qPCR data are presented as fold above the level for IgG. Results are representative of three independent experiments and show means ± standard deviations. (C) ChIP-qPCR for the active H3K4me3 mark at Cp in untreated and olaparib-treated (PARPi) LCLs. qPCR data are presented as fold above the level for IgG. Results are representative of three independent experiments and show means ± standard deviations.