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. 2018 Aug 29;92(18):e00663-18. doi: 10.1128/JVI.00663-18

FIG 7.

FIG 7

Schematic model showing the modulation of the cyclin D2 function by EBNA3C. EBNA3C associates with cyclin D2 and enhances its stability at the protein level through inhibition of its ubiquitin-mediated degradation. The EBNA3C-cyclin D2 interaction ultimately drives cell proliferation, which leads to lymphomagenesis.