FIG 3.
αS inclusion pathology in M83+/− injected mice. M83+/− mice were injected unilaterally in the sciatic nerve with the indicated homogenates and harvested at the end stage of disease (mfib αS and hfib αS E46K) or at 6 months p.i. (PBS, human Δ71–82 αS, and WT SOD1 fibs). Spinal cords were stained with a conformation-specific antibody against αS, Syn 506 (a), and an antibody specific for cytoplasmic Lewy body inclusions, p62/Sqstm1 (b).