SIV DNA persistence in LN CD4+ T cells of ART-treated SIV-infected RM infants and adults. (A) On-ART SIV DNA levels in subsets of CD4+ T cells (naive, SCM, CM, and TFH CD4+ T cells) sorted from superficial (axillary and inguinal), mesenteric, and retroperitoneal LN. The horizontal lines represent medians. (B) Relative contributions of CD4+ T cell subsets (naive, SCM, CM/TM, and EM CD4+ T cells) to the total LN CD4+ T cell pool. (C) Relative contributions of CD4+ T cell subsets (naive, SCM, CM/TM, and EM CD4+ T cells) to the total LN CD4+ T cell SIV reservoir.