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Magnitude of SIV Gag response in control and CBD1/CBM-vaccinated monkeys after SHIV challenge. PBMCs from CBD1/CBM-vaccinated macaques (30164, 30237, 30317, 30788, and 30809) and control macaques (27085R, 30154, 30713, 31003, 31004, 30991) were stimulated with SIV Gag antigen, and the numbers of IL-2 (A) and IFN-γ (B) ELISpots were assessed at different weeks postchallenge. Data are shown as spot-forming cells (SFC) per million PBMCs minus the background (medium alone).
