Effect of paeoniflorin on E-cadherin, Vimentin, and HDAC2 expression at the RNA level in HCT116 and SW480 cells. PCR was used to detect E-cadherin, Vimentin, and HDAC2 expression of RNA levels in HCT116 and SW480 cells after paeoniflorin treatment. With the increase of paeoniflorin concentration, E-cadherin was upregulated, while Vimentin and HDAC2 were downregulated in a dose-dependent manner (n=3). * P<0.05; ** P<0.01.