TABLE 2.
Mutation | % of sequence with the mutationb |
|
---|---|---|
P1 | P3 | |
D522E | ND | ND |
T544I | 7.7 | 10.3 |
H549R | 42.7 | 64.2 |
D552N | 8.9 | 7.6 |
R574H | ND | ND |
I584L | ND | ND |
Stocks were serially passaged in VeroE6 cells (MOI of 0.001).
As determined by Sanger sequencing. ND, the nucleotide peak representing this mutation was not detected in the trace file.