FIG 7.

PAA inhibits viral DNA replication and late protein expression induced by ZEBRA. (A) qPCR for relative abundance of viral DNA. In each experiment qPCR was performed on the same cells used for Western blot analysis. Each triangle represents one replicate. The horizontal line denotes the mean. P values were determined using pairwise Student's t tests with Dunnett's correction for multiple comparisons compared to results with the untreated control. **, P ≤ 0.0021. (B) Western blot of BZKO cells harvested 48 h after transfection with control vector, ZEBRA, or AP-1(A/S) and treated with PAA (500 μM) immediately after transfection. The blot is representative of three experiments.