Table 1.
Phthalate (parent) |
Tolerable daily intakes (μg/kg/d) |
Uncertainty factors |
Metabolite | Limit of detection in NHANES (ng/mL) |
Number of samples below the limit of detection (%) |
---|---|---|---|---|---|
di-n-butyl phthalate (DBP) |
10a | 200a | monobutyl phthalate (MBP)g | 0.4 | 43 (1.6) |
diisobutyl phthalate (DIBP) |
1250b | 100b | monoisobutyl phthalate (MIBP)g | 0.8 | 72 (2.7) |
butyl benzyl phthalate (BBP) |
500c | 100c | monobenzyl phthalate (MBZP)g | 0.3 | 63 (2.4) |
di(2- ethylhexyl) phthalate (DEHP) |
50d | 100d | mono(2-ethyl-5-carboxypentyl) phthalate (MECPP)g | 0.4 | 6 (0.2) |
mono(2-ethyl-5-oxohexyl) phthalate (MEOHP)g | 0.2 | 13 (0.5) | |||
mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)g | 0.4 | 9 (0.3) | |||
mono(2-ethylhexyl) phthalate (MEHP)g | 0.8 | 1003 (37.66) | |||
diisononyl phthalate (DINP) |
150e | 100e | monoisononyl phthalate (MINP)h | 0.9 | 1586 (59.56) |
mono(carboxyoctyl) phthalate (MCOP)g | 0.3 | 3 (0.1) | |||
diisodecyl phthalate (DIDP) |
130f | 100f | mono(carboxynonyl) phthalate (MCNP)h | 0.2 | 32 (1.2) |
(EFSA, 2005a);
(Saillenfait et al., 2008);
(EFSA, 2005b);
(EFSA, 2005c);
(EFSA, 2005d);
(CPSC, 2010);
(Qian et al., 2015) only.