Table 1.
Subject demographics and neuropathologic assessment
Case | Age in years |
Gender | Break stage |
CERAD plaque score |
Level of AD pathologic change |
CAA |
---|---|---|---|---|---|---|
AD with CAA type 1 |
||||||
1 | 79 | M | VI | 3 | High | Severe |
2 | 78 | F | VI | 2 | High | Severe |
3 | 68 | F | VI | 3 | High | Severe |
4 | 101 | M | V | 2 | High | Severe |
5 | 73 | M | V | 2 | High | Severe |
6 | 75 | M | VI | 3 | High | Severe |
7 | 76 | M | VI | 1 | Intermediate | Moderate |
8 | 80 | M | VI | 3 | High | Severe |
AD with CAA type 2 |
||||||
1 | 76 | M | VI | 3 | High | Severe |
2 | 93 | F | VI | 3 | High | Moderate |
3 | 69 | F | VI | 3 | High | Severe |
4 | 86 | F | IV-V | 3 | Intermediate-high Moderate | |
5 | 82 | F | VI | 3 | High | Severe |
6 | 78 | M | VI | 2 | High | Severe |
7 | 68 | M | VI | 2 | High | Severe |
8 | 64 | F | VI | 1 | Intermediate | Severe |
9 | 96 | F | VI | 2 | High | Moderate |
10 | 70 | M | VI | 2 | High | Moderate |
AD without CAA |
||||||
1 | 65 | F | VI | 2–3 | High | No CAA |
2 | 115 | F | IV-V | 2 | Intermediate-high No CAA | |
3 | 81 | F | V | 3 | High | No CAA |
4 | 63 | VI, also DLBD | 3 | High | No CAA | |
5 | 61 | M | VI | 3 | High | No CAA |
6 | 70 | M | VI | 3 | High | No CAA |
7 | 93 | M | V-VI | 1–2 | Intermediate-high | No CAA |
Nondemented elderly |
||||||
1 | 71 | M | II | 0 | Low | No CAA |
2 | 76 | F | <IV | 0 | Not | No CAA |
3 | 66 | M | I | 0 | Low | No CAA |
4 | 79 | F | II | 0 | Not | No CAA |
5 | 64 | F | <IV | 0 | Not | No CAA |
6 | 67 | M | I | 0 | Not | No CAA |
7 | 75 | F | III-IV | 0 | Low | No CAA |
8 | 65 | M | I-II | 0 | Not | No CAA |
9 | 75 | M | I | 0 | Not | No CAA |
10 | 89 | M | <IV | 0 | Low | No CAA |
Key: AD, Alzheimer disease; CERAD, Consortium to Establish a Registry for AD; CAA, cerebral amyloid angiopathy; DLBD, diffuse Lewy body disease.