Table 2.

Correlation of SIRT1, MMP2, and FOXO3a with other parameters in the malignant group.

	SIRT1		MMP2		FOXO3a
	r	P-value	r	P-value	r	P-value
Age	−0.39	0.05	−0.77	<0.001	-05	0.01
Grade	0.55	0.005	0.12	0.57	0.005	0.98
Stage	0.48	0.02	0.52	0.01	0.435	0.03
Tumor size	0.36	0.08	0.03	0.87	0.103	0.63
CA15.3	−0.44	0.03	−0.4	0.05	-0.6	0.002
CEA	−0.34	0.10	−0.45	0.02	−0.65	0.001
Lymph node	0.67	<0.001	0.71	<0.001	0.51	0.01
SIRT1	–	–	0.75	<0.001	0.8	<0.001
MMP2	0.75	<0.001	–	–	0.7	<0.001
FOXO3a	0.8	<0.001	0.7	<0.001	–	–

CA: cancer antigen, CEA: carcinoembryonic antigen, SIRT1: sirtuin 1, MMP2: matrix metalloproteinases, FOXO3a: forkhead box O3a. Significance was considered at P < 0.05.