Table 5.
Serum parameters and glomerular filtration rate (GFR) for both groups
| Variable | TDF group (n = 57) | Non-TDF group (n = 47) | P value* |
|---|---|---|---|
| At baseline | |||
| Serum creatinine (μmol/L) | 99.4 ± 9.8 | 97.4 ± 8.9 | 0.298 |
| GFR (mL/min/1.73 m2) | 105 ± 47 | 110 ± 54 | 0.656 |
| Serum glucose (mmol/L) | 5.19 ± 1.00 | 5.18 ± 0.85 | 0.957 |
| At 16th wk | |||
| Serum creatinine (μmol/L) | 136 ± 23 | 129 ± 18 | 0.109 |
| GFR (mL/min/1.73 m2) | 78.6 ± 28.7 | 83.5 ± 27.2 | 0.383 |
| Serum glucose (mmol/L) | 5.69 ± 0.97 | 6.05 ± 1.07 | 0.072 |
| At 24th wk | |||
| Serum creatinine (μmol/L) | 154 ± 55 | 136 ± 58 | 0.083 |
| GFR (mL/min/1.73 m2) | 64.7 ± 26.2 | 73.2 ± 22.3 | 0.083 |
| Serum glucose | 5.87 ± 0.86 | 5.61 ± 0.74 | 0.108 |
Data are presented as mean ± standard deviation.
TDF, tenofovir disoproxil fumarate.