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. 2018 Sep 17;12:3013–3019. doi: 10.2147/DDDT.S164553

Table 1.

Baseline characteristics of included trials

Author Patient enrolled Phase Treatment regimes Median age, years Median PFS, months No for analysis
Audeh et al, 201027 57 II Olaparib 400 mg bid 54 NR 57
Gelmon et al, 201126 65 II Olaparib 400 mg bid 58 7.1 65
Kaye et al, 201225 97 II Olaparib 200 mg bid 58.5 6.5 64
Pegylated liposomal doxorubicin 53 7.1 33
Ledermann et al, 201224 265 II Olaparib 400 mg bid po 58 8.4 136
Placebo 59 4.8 128
Liu et al, 201431 90 II Olaparib 400 mg bid po 57.8 9 46
Coleman et al, 201530 50 II Veliparib 400 mg bid po 57 8.18 50
Bell-McGuinn et al, 201629 12 II Iniparib 8 mg/kg NR NR 12
Domchek et al, 201628 154 II Olaparib 400 mg bid po 58 NR 154
Mirza et al, 201621 553 III Niraparib 300 mg qd po 57 21 367
Placebo 58 5.5 179
Pujade-Lauraine et al, 201723 295 III Olaparib 150 mg bid po 56 19.1 195
Placebo 56 5.5 99
Swisher et al, 201732 206 II Rucaparib 600 mg bid po NR NR 206
Coleman et al, 201722 564 III Rucaparib 600 mg bid po 61 16.6 375
Placebo 62 5.4 189

Abbreviations: NR, not reported; PFS, progression-free survival; Bid, bis in die; Po, per os.