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. Author manuscript; available in PMC: 2018 Sep 20.
Published in final edited form as: Neuromethods. 2016;113:193–211. doi: 10.1007/978-1-4939-3411-9_10

Figure 1.

Figure 1

Binomial model of synaptic transmission. (a) Postsynaptic currents for a synapse with N = 5, Q = -20 pA at P = 0.1, 0.5 and 0.9 were simulated stochastically (20 superimposed traces in grey and average trace of 200 events in black). (b) The dots represent the theoretical values of variance and mean amplitude at the 3 different release probabilities tested. The empty squares are values from a set of 200 simulated postsynaptic currents. The variance-mean relationship of the theoretical values was fitted using equation (3). (modified from ref 58 with permission from Elsevier)