Table 2.
The histopathological lesions observed by light microscopy and electron microscopy in the studied groups.
| Lesions | Group 1 | Group 2 | Group 3 | Group 4 |
|---|---|---|---|---|
| Liver lesions observed by Light microscope | ||||
| Hemorrhage | ++ | – | – | – |
| Congestion | ++++ | + | – | – |
| Vacuolar degeneration | ++++ | + | – | – |
| Mononuclear infiltration | +++ | – | – | – |
| Kupffer cell proliferation | +++ | – | – | – |
| Liver lesions observed by EM | ||||
| Mitochondrial swelling | ## | # | – | – |
| Fatty globules | ### | # | – | – |
| Nanoparticles in Kupffer cells and hepatocytes | ## | – | – | – |
| Testicular lesions observed by Light microscope | ||||
| Interstitial edema | ++++ | + | – | – |
| Congestion | ++++ | – | – | – |
| Degenerative changes | ++++ | – | – | – |
| Testicular lesions observed by EM | ||||
| Presence of nanoparticles | ### | – | – | – |
Presence of lesions by light microscopy expressed by; – (0 rats), + (1–3 rats), ++ (4–6 rats), +++ (7–9 rats), ++++ (10–12 rats). Presence of lesions by EM expressed by; – (0 rats), #(1 rats), ## (2 rats), ### (3 rats).