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. 2018 Sep 20;13(9):e0199237. doi: 10.1371/journal.pone.0199237

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© 2018 Ma et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — (A) Area-proportional Venn diagram depicts the overlap of the identified serum proteins between N- and CSD-group rats from mass spectrometry measurements. A total of 309 non-redundant proteins with 297 and 298 proteins were identified in N- and CSD-groups, respectively. 286 proteins were found in both groups. (B) A heat map analysis of the DAPs between N- and CSD-group. 117 proteins displayed more than 1.8-fold quantitative alteration, of which 49 proteins were upregulated and 68 were downregulated in the CSD-group compared to that of the N-group. Color depth from blue to red indicates the intensity detected by LC-MS analysis from low to high.