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. 2018 Sep 20;14(9):e1007102. doi: 10.1371/journal.ppat.1007102

Fig 8. MntH2 and EfaCBA promote virulence of E. faecalis in a murine CAUTI model.

Fig 8

OG1RF and its derivatives were inoculated into the bladder of mice immediately after catheter implantation (n = 10 to 22). After 24 hours, animals were euthanized, and bacterial burdens in (A) bladders and (B) catheters determined. Graphs show total CFU recovered from these sites, and each symbol represents an individual mouse. Symbols on the dashed line indicate that recovery was below the limit of detection (LOD, 40 CFU). Data were pooled from at least two independent experiments, and the median value is shown as a horizontal line. Two-tailed Mann-Whitney U tests were performed to determine significance (**p < 0.005, ****p < 0.0001).